The effect of carbamazepine on bone structure and strength in control and osteogenesis imperfecta (Col1a2 (+/p.G610C) ) mice

The inherited brittle bone disease osteogenesis imperfecta (OI) is commonly caused by COL1A1 and COL1A2 mutations that disrupt the collagen I triple helix. This causes intracellular endoplasmic reticulum (ER) retention of the misfolded collagen and can result in a pathological ER stress response. A...

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Detalles Bibliográficos
Autores principales: Blank, Martha, McGregor, Narelle E., Rowley, Lynn, Kung, Louise H. W., Crimeen‐Irwin, Blessing, Poulton, Ingrid J., Walker, Emma C., Gooi, Jonathan H., Lamandé, Shireen R., Sims, Natalie A., Bateman, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279589/
https://www.ncbi.nlm.nih.gov/pubmed/35701367
http://dx.doi.org/10.1111/jcmm.17437

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