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Celecoxib attenuates hepatosteatosis by impairing de novo lipogenesis via Akt‐dependent lipogenic pathway
Mounting evidence indicates that hepatic de novo lipogenesis is a common abnormality in non‐alcoholic fatty liver disease (NAFLD) patients. We investigated whether a selective COX‐2 inhibitor, celecoxib, alleviates hepatic steatosis by targeting an Akt‐driven lipogenic pathway. We estimated the effi...
Autores principales: | Zhang, Cong, Lu, Yuzhen, Song, Yingying, Chen, Liang, Hu, Junjie, Meng, Yan, Chen, Xin, Li, Shan, Zheng, Guohua, Qiu, Zhenpeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279593/ https://www.ncbi.nlm.nih.gov/pubmed/35713152 http://dx.doi.org/10.1111/jcmm.17435 |
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