Role of ADAM10 and ADAM17 in the Regulation of Keratinocyte Adhesion in Pemphigus Vulgaris

The severe autoimmune blistering disease Pemphigus vulgaris (PV) is mainly caused by autoantibodies (IgG) against desmoglein (Dsg) 3 and Dsg1. The mechanisms leading to the development of blisters are not fully understood, but intracellular signaling seems to play an important role. Sheddases ADAM10...

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Detalles Bibliográficos
Autores principales: Kugelmann, Daniela, Anders, Maresa, Sigmund, Anna M., Egu, Desalegn T., Eichkorn, Ramona A., Yazdi, Amir S., Sárdy, Miklós, Hertl, Michael, Didona, Dario, Hashimoto, Takashi, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279611/
https://www.ncbi.nlm.nih.gov/pubmed/35844545
http://dx.doi.org/10.3389/fimmu.2022.884248

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