Characterization of a novel bispecific antibody targeting tissue factor-positive tumors with T cell engagement

T cell engaging bispecific antibody (TCB) is an effective immunotherapy for cancer treatment. Through co-targeting CD3 and tumor-associated antigen (TAA), TCB can redirect CD3(+) T cells to eliminate tumor cells regardless of the specificity of T cell receptor. Tissue factor (TF) is a TAA that invol...

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Detalles Bibliográficos
Autores principales: Pan, Zhidi, Chen, Jie, Xiao, Xiaodong, Xie, Yueqing, Jiang, Hua, Zhang, Baohong, Lu, Huili, Yuan, Yunsheng, Han, Lei, Zhou, Yuexian, Zong, Huifang, Wang, Lei, Sun, Rui, Zhu, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279644/
https://www.ncbi.nlm.nih.gov/pubmed/35847491
http://dx.doi.org/10.1016/j.apsb.2021.10.028

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