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RNA-SSNV: A Reliable Somatic Single Nucleotide Variant Identification Framework for Bulk RNA-Seq Data

The usage of expressed somatic mutations may have a unique advantage in identifying active cancer driver mutations. However, accurately calling mutations from RNA-seq data is difficult due to confounding factors such as RNA-editing, reverse transcription, and gap alignment. In the present study, we...

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Detalles Bibliográficos
Autores principales: Long, Qihan, Yuan, Yangyang, Li, Miaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279659/
https://www.ncbi.nlm.nih.gov/pubmed/35846154
http://dx.doi.org/10.3389/fgene.2022.865313

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