Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy

Alzheimer's disease (AD), characterized by the accumulation of protein aggregates including phosphorylated Tau aggregates, is the most common neurodegenerative disorder with limited therapeutic agents. Autophagy plays a critical role in the degradation of phosphorylated Tau aggregates, and tran...

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Detalles Bibliográficos
Autores principales: Yang, Chuanbin, Su, Chengfu, Iyaswamy, Ashok, Krishnamoorthi, Senthil Kumar, Zhu, Zhou, Yang, Sichang, Tong, Benjamin Chunkit, Liu, Jia, Sreenivasmurthy, Sravan G., Guan, Xinjie, Kan, Yuxuan, Wu, Aston Jiaxi, Huang, Alexis Shiying, Tan, Jieqiong, Cheung, Kingho, Song, Juxian, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279716/
https://www.ncbi.nlm.nih.gov/pubmed/35847498
http://dx.doi.org/10.1016/j.apsb.2022.01.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279716/
https://www.ncbi.nlm.nih.gov/pubmed/35847498
http://dx.doi.org/10.1016/j.apsb.2022.01.017

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