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Human IL-17 and TNF-α Additively or Synergistically Regulate the Expression of Proinflammatory Genes, Coagulation-Related Genes, and Tight Junction Genes in Porcine Aortic Endothelial Cells

Immune rejection is the major limitation for porcine xenograft survival in primate recipients. Proinflammatory cytokines play important roles in immune rejection and have been found to mediate the pathological effects in various clinical and experimental transplantation trials. IL-17 and TNF-α play...

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Detalles Bibliográficos
Autores principales: Li, Weilong, Chen, Pengfei, Zhao, Yanli, Cao, Mengtao, Hu, Wenjun, Pan, Litao, Sun, Huimin, Huang, Dongsheng, Wu, Hanxi, Song, Zhuoheng, Zhong, Huanli, Mou, Lisha, Luan, Shaodong, Chen, Xiehui, Gao, Hanchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279740/
https://www.ncbi.nlm.nih.gov/pubmed/35844613
http://dx.doi.org/10.3389/fimmu.2022.857311