Cargando…

Icariin promotes the repair of bone marrow mesenchymal stem cells in rabbit knee cartilage defects via the BMP/Smad pathway

BACKGROUND: Icariin (ICA) has been widely used in the treatment of osteoporosis. However, the potential mechanism of its critical role in repairing knee cartilage damage still needs to be further clarified. METHODS: First, rabbit bone marrow mesenchymal stem cells (BMSCs) were isolated, cultured, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiao, Feng, Tang, Wang, Wang, Jie, Liu, Donghua, Zhang, Hongyi, Tang, Dongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279777/ https://www.ncbi.nlm.nih.gov/pubmed/35845525 http://dx.doi.org/10.21037/atm-22-2515

Ejemplares similares

Icariin accelerates cartilage defect repair by promoting chondrogenic differentiation of BMSCs under conditions of oxygen‐glucose deprivation
por: Tang, Wang, et al.
Publicado: (2021)

Icariin-conditioned serum engineered with hyaluronic acid promote repair of articular cartilage defects in rabbit knees
por: Zhang, Juntao, et al.
Publicado: (2019)

Correction : Icariin-conditioned serum engineered with hyaluronic acid promote repair of articular cartilage defects in rabbit knees
por: Zhang, Juntao, et al.
Publicado: (2023)

Icariin-conditioned serum combined with chitosan attenuates cartilage injury in rabbit knees with osteochondral defect
por: Zhang, Juntao, et al.
Publicado: (2023)

Repair of osteochondral defect using icariin-conditioned serum combined with chitosan in rabbit knees
por: Zhang, Juntao, et al.
Publicado: (2020)

Correction: Repair of osteochondral defect using icariin-conditioned serum combined with chitosan in rabbit knees
por: Zhang, Juntao, et al.
Publicado: (2022)

Icariin Promotes the Migration of BMSCs In Vitro and In Vivo via the MAPK Signaling Pathway
por: Jiao, Feng, et al.
Publicado: (2018)

Icariin-Loaded Hydrogel Regulates Bone Marrow Mesenchymal Stem Cell Chondrogenic Differentiation and Promotes Cartilage Repair in Osteoarthritis
por: Zhu, Yuefeng, et al.
Publicado: (2022)

The Functions of BMP3 in Rabbit Articular Cartilage Repair
por: Zhang, Zhe, et al.
Publicado: (2015)

Naringin and bone marrow mesenchymal stem cells repair articular cartilage defects in rabbit knees through the transforming growth factor-β superfamily signaling pathway
por: Ye, Chao, et al.
Publicado: (2020)

Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits
por: Liu, Hao, et al.
Publicado: (2021)

Electrospun Icariin-Loaded Core-Shell Collagen, Polycaprolactone, Hydroxyapatite Composite Scaffolds for the Repair of Rabbit Tibia Bone Defects
por: Zhao, Hongbin, et al.
Publicado: (2020)

Matrigel scaffold combined with Ad-hBMP7-transfected chondrocytes improves the repair of rabbit cartilage defect
por: Xia, Xiaopeng, et al.
Publicado: (2017)

Mechanism of Action of Icariin in Bone Marrow Mesenchymal Stem Cells
por: Yang, Aofei, et al.
Publicado: (2019)

Morphological Observation on Critical-Sized Cranial Defect Repaired by Icariin and Autologous Concentrate Growth Factors in Rabbits
por: Li, Gang, et al.
Publicado: (2017)

The Effect of Human Bone Marrow Mesenchymal Stem Cell-Derived Exosomes on Cartilage Repair in Rabbits
por: Yang, Hongwei, et al.
Publicado: (2022)

Effect of Warm Acupuncture Combined with Bone Marrow Mesenchymal Stem Cells Transplantation on Cartilage Tissue in Rabbit Knee Osteoarthritis
por: Liu, Jun-wei, et al.
Publicado: (2021)

BMP-7 accelerates the differentiation of rabbit mesenchymal stem cells into cartilage through the Wnt/β-catenin pathway
por: Fu, Hong-Dan, et al.
Publicado: (2017)

Effect of Icariin on Engineered 3D-Printed Porous Scaffolds for Cartilage Repair
por: Kankala, Ranjith Kumar, et al.
Publicado: (2018)

Combination of chondrocytes and chondrons improves extracellular matrix production to promote the repairs of defective knee cartilage in rabbits
por: Duan, Wangping, et al.
Publicado: (2021)

Icariin promotes directed chondrogenic differentiation of bone marrow mesenchymal stem cells but not hypertrophy in vitro
por: WANG, ZHI CONG, et al.
Publicado: (2014)

Chordin-Like 1 Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells Through Enhancing BMP4-SMAD Pathway
por: Liu, Tao, et al.
Publicado: (2019)

Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects
por: Liu, Tianlin, et al.
Publicado: (2016)

Long-Term Results of Cartilage Repair after Allogeneic Transplantation of Cartilaginous Aggregates Formed from Bone Marrow–Derived Cells for Large Osteochondral Defects in Rabbit Knees
por: Yoshioka, Tomokazu, et al.
Publicado: (2013)

Combination of bone marrow mesenchymal stem cells and cartilage fragments contribute to enhanced repair of osteochondral defects
por: Abbas, Mohammed
Publicado: (2017)

Repair of articular cartilage defects with intra-articular injection of autologous rabbit synovial fluid-derived mesenchymal stem cells
por: Jia, Zhaofeng, et al.
Publicado: (2018)

PLGA scaffold carrying icariin to inhibit the progression of osteoarthritis in rabbits
por: Zhao, Chang Fu, et al.
Publicado: (2019)

Immunohistological Localization of BMP-2, BMP-7, and Their Receptors in Knee Joints with Focal Cartilage Lesions
por: Schmal, Hagen, et al.
Publicado: (2012)

Improvement of Cartilage Repair With Biologically Regulated Marrow Stimulation by Blocking TGF-β1 in A Rabbit Osteochondral Defect Model
por: Utsunomiya, Hajime, et al.
Publicado: (2019)

Icariin Prevents Cartilage and Bone Degradation in Experimental Models of Arthritis
por: Chao Wei, Chen, et al.
Publicado: (2016)

Comparison between Intra-Articular Injection of Infrapatellar Fat Pad (IPFP) Cell Concentrates and IPFP-Mesenchymal Stem Cells (MSCs) for Cartilage Defect Repair of the Knee Joint in Rabbits
por: Han, Yaguang, et al.
Publicado: (2021)

Parathyroid Hormone-Induced Bone Marrow Mesenchymal Stem Cell Chondrogenic Differentiation and its Repair of Articular Cartilage Injury in Rabbits
por: Chen, Yushu, et al.
Publicado: (2016)

Icariin Improves the Viability and Function of Cryopreserved Human Nucleus Pulposus-Derived Mesenchymal Stem Cells
por: Chen, Sheng, et al.
Publicado: (2018)

Icariin promotes osteogenic differentiation of BMSCs by upregulating BMAL1 expression via BMP signaling
por: Huang, Zengfa, et al.
Publicado: (2020)

Extracellular calcium promotes bone formation from bone marrow mesenchymal stem cells by amplifying the effects of BMP-2 on SMAD signalling
por: Aquino-Martínez, Rubén, et al.
Publicado: (2017)

KR-12-a6 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via BMP/SMAD signaling
por: Fu, Lanqing, et al.
Publicado: (2020)

Icariin Regulates the Bidirectional Differentiation of Bone Marrow Mesenchymal Stem Cells through Canonical Wnt Signaling Pathway
por: Huang, Jun-ming, et al.
Publicado: (2017)

miR-765 inhibits the osteogenic differentiation of human bone marrow mesenchymal stem cells by targeting BMP6 via regulating the BMP6/Smad1/5/9 signaling pathway
por: Wang, Tao, et al.
Publicado: (2020)

All-arthroscopic AMIC procedure for repair of cartilage defects of the knee
por: Piontek, Tomasz, et al.
Publicado: (2011)

Investigation of the Effects of Intra-articular Tranexamic Acid on Intact Cartilage Tissue and Cartilage Formation in Osteochondral Defects of the Rabbit Knee: An Experimental Study
por: Bi̇ri̇si̇k, Fevzi̇, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bjfb312f20ti5n08343g7cbc67