Cargando…

MiR-20a: a mechanosensitive microRNA that regulates fluid shear stress-mediated osteogenic differentiation via the BMP2 signaling pathway by targeting BAMBI and SMAD6

BACKGROUND: MicroRNAs (miRNAs) are crucial regulators of diverse biological and pathological processes. This study aimed to investigate the role of microRNA 20a (miR-20a) in fluid shear stress (FSS)-mediated osteogenic differentiation. METHODS: In the present study, we subjected osteoblast MC3T3-E1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peng, Zhuli, Mai, Zhihui, Xiao, Feng, Liu, Guanqi, Wang, Yixuan, Xie, Shanshan, Ai, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279817/ https://www.ncbi.nlm.nih.gov/pubmed/35845505 http://dx.doi.org/10.21037/atm-22-2753

Ejemplares similares

Single Bout Short Duration Fluid Shear Stress Induces Osteogenic Differentiation of MC3T3-E1 Cells via Integrin β1 and BMP2 Signaling Cross-Talk
por: Mai, Zhihui, et al.
Publicado: (2013)

BAMBI
por: Cittolin, Sergio
Publicado: (1977)

miR-20a-5p contributes to osteogenic differentiation of human dental pulp stem cells by regulating BAMBI and activating the phosphorylation of Smad5 and p38
por: Cen, Xiao, et al.
Publicado: (2021)

Suppressing MicroRNA-30b by Estrogen Promotes Osteogenesis in Bone Marrow Mesenchymal Stem Cells
por: Liu, Guanqi, et al.
Publicado: (2019)

Correction: miR-20a-5p contributes to osteogenic differentiation of human dental pulp stem cells by regulating BAMBI and activating the phosphorylation of Smad5 and p38
por: Cen, Xiao, et al.
Publicado: (2022)

Bambi : amigos del bosque /
Publicado: (1992)

Bambi : historia de una vida del bosque
por: Salten, Félix, 1868-1945
Publicado: (2003)

Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6
por: Miura, Shigenori, et al.
Publicado: (2015)

Bambi : historia de una vida en el bosque
por: Salten, Félix, 1869-1945
Publicado: (1965)

Expression and Function of BMP and Activin Membrane-Bound Inhibitor (BAMBI) in Chronic Liver Diseases and Hepatocellular Carcinoma
por: Weber, Florian, et al.
Publicado: (2023)

Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation
por: Sautchuk, Rubens, et al.
Publicado: (2022)

IGF1 potentiates BMP9-induced osteogenic differentiation in mesenchymal stem cells through the enhancement of BMP/Smad signaling
por: Chen, Liang, et al.
Publicado: (2016)

Mechanosensitive TRPM7 mediates shear stress and modulates osteogenic differentiation of mesenchymal stromal cells through Osterix pathway
por: Liu, Yi-Shiuan, et al.
Publicado: (2015)

Adipose-specific BMP and activin membrane-bound inhibitor (BAMBI) deletion promotes adipogenesis by accelerating ROS production
por: Chen, Xiaochang, et al.
Publicado: (2020)

Genistein Promotion of Osteogenic Differentiation through BMP2/SMAD5/RUNX2 Signaling
por: Dai, Jin, et al.
Publicado: (2013)

miR-21 synergizes with BMP9 in osteogenic differentiation by activating the BMP9/Smad signaling pathway in murine multilineage cells
por: SONG, QILING, et al.
Publicado: (2015)

Notch signaling and fluid shear stress in regulating osteogenic differentiation
por: Zhao, Yuwen, et al.
Publicado: (2022)

Inhibition of BAMBI reduces the viability and motility of colon cancer via activating TGF-β/Smad pathway in vitro and in vivo
por: Yu, Wenzhen, et al.
Publicado: (2017)

Inhibition of BAMBI reduces the viability and motility of colon cancer via activating TGF-β/Smad pathway in vitro and in vivo
por: Yu, Wenzhen, et al.
Publicado: (2021)

Micromotion Derived Fluid Shear Stress Mediates Peri‐Electrode Gliosis through Mechanosensitive Ion Channels
por: Trotier, Alexandre, et al.
Publicado: (2023)

Notch signaling pathway promotes osteogenic differentiation of mesenchymal stem cells by enhancing BMP9/Smad signaling
por: Cao, Junjie, et al.
Publicado: (2017)

Los hijos de bambi : historia de una familia del bosque
por: Salten, Félix, 1869-1945
Publicado: (1965)

Mechanosensitive miR‐100 coordinates TGFβ and Wnt signaling in osteocytes during fluid shear stress
por: Dole, Neha S., et al.
Publicado: (2021)

Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors
por: Luo, Xiao, et al.
Publicado: (2012)

BMP-4, TGF-β and Smad3 as Modulators of Synovial Fluid Cells Viability
por: Sousa, Eduardo Branco de, et al.
Publicado: (2021)

Kangquan Recipe Regulates the Expression of BAMBI Protein via the TGF-β/Smad Signaling Pathway to Inhibit Benign Prostatic Hyperplasia in Rats
por: Chen, Wenfan, et al.
Publicado: (2019)

Shear elegance: A novel screen uncovers a mechanosensitive GPCR
por: Lam, Ruby M., et al.
Publicado: (2018)

The antimicrobial peptide KR-12 promotes the osteogenic differentiation of human bone marrow stem cells by stimulating BMP/SMAD signaling
por: Li, Hui, et al.
Publicado: (2018)

MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway
por: Liu, Hongxia, et al.
Publicado: (2018)

BAMBI Is Expressed in Endothelial Cells and Is Regulated by Lysosomal/Autolysosomal Degradation
por: Xavier, Sandhya, et al.
Publicado: (2010)

Shear Stress Alterations Activate BMP4/pSMAD5 Signaling and Induce Endothelial Mesenchymal Transition in Varicose Veins
por: Chandran Latha, Karthika, et al.
Publicado: (2021)

Association of Bone Morphogenetic Protein (BMP)/Smad Signaling Pathway with Fracture Healing and Osteogenic Ability in Senile Osteoporotic Fracture in Humans and Rats
por: Liu, De-Bao, et al.
Publicado: (2018)

KR-12-a6 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via BMP/SMAD signaling
por: Fu, Lanqing, et al.
Publicado: (2020)

Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities
por: Berasi, Stephen P, et al.
Publicado: (2011)

Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway
por: Cui, Qi, et al.
Publicado: (2019)

Ablation of Fam20c causes amelogenesis imperfecta via inhibiting Smad dependent BMP signaling pathway
por: Liu, Jing, et al.
Publicado: (2020)

Brief Autism Mealtime Behavior Inventory (BAMBI): Italian Translation and Validation
por: Lamboglia, Antonella, et al.
Publicado: (2023)

Prediction of Mechanosensitive Genes in Vascular Endothelial Cells Under High Wall Shear Stress
por: Shen, Lei, et al.
Publicado: (2022)

Endothelial microparticles: A mechanosensitive regulator of vascular homeostasis and injury under shear stress
por: Feng, Shuo, et al.
Publicado: (2022)

Downregulation of circRNA DMNT3B contributes to diabetic retinal vascular dysfunction through targeting miR-20b-5p and BAMBI
por: Zhu, Ke, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6ec7o8dig2qfkmc40b47splln1