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WX-0593 combined with an epithelial growth factor receptor (EGFR) monoclonal antibody in the treatment of xenograft tumors carrying triple EGFR mutations

BACKGROUND: To evaluate the safety and therapeutic efficacy of WX-0593, a newly developed potent anaplastic lymphoma kinase (ALK) inhibitor, in combination with an epithelial growth factor receptor (EGFR) monoclonal antibody (QL1203 or Vectibix) for the treatment of xenograft tumors carrying mutant...

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Detalles Bibliográficos
Autores principales: Zheng, Qingmei, Chen, Dongmei, Wang, Xinmei, Yang, Yingying, Zhao, Shuyong, Dong, Xin, Ma, Cuicui, Zhang, Xin, Duan, Huicheng, Sun, Yan, Zheng, Shansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279820/
https://www.ncbi.nlm.nih.gov/pubmed/35845484
http://dx.doi.org/10.21037/atm-22-2780