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WX-0593 combined with an epithelial growth factor receptor (EGFR) monoclonal antibody in the treatment of xenograft tumors carrying triple EGFR mutations
BACKGROUND: To evaluate the safety and therapeutic efficacy of WX-0593, a newly developed potent anaplastic lymphoma kinase (ALK) inhibitor, in combination with an epithelial growth factor receptor (EGFR) monoclonal antibody (QL1203 or Vectibix) for the treatment of xenograft tumors carrying mutant...
Autores principales: | Zheng, Qingmei, Chen, Dongmei, Wang, Xinmei, Yang, Yingying, Zhao, Shuyong, Dong, Xin, Ma, Cuicui, Zhang, Xin, Duan, Huicheng, Sun, Yan, Zheng, Shansong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279820/ https://www.ncbi.nlm.nih.gov/pubmed/35845484 http://dx.doi.org/10.21037/atm-22-2780 |
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