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Biological impact of iberdomide in patients with active systemic lupus erythematosus

OBJECTIVES: Iberdomide is a high-affinity cereblon ligand that promotes proteasomal degradation of transcription factors Ikaros (IKZF1) and Aiolos (IKZF3). Pharmacodynamics and pharmacokinetics of oral iberdomide were evaluated in a phase 2b study of patients with active systemic lupus erythematosus...

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Detalles Bibliográficos
Autores principales:	Lipsky, Peter E, van Vollenhoven, Ronald, Dörner, Thomas, Werth, Victoria P, Merrill, Joan T, Furie, Richard, Petronijevic, Milan, Velasco Zamora, Benito, Majdan, Maria, Irazoque-Palazuelos, Fedra, Terbrueggen, Robert, Delev, Nikolay, Weiswasser, Michael, Korish, Shimon, Stern, Mark, Hersey, Sarah, Ye, Ying, Gaudy, Allison, Liu, Zhaohui, Gagnon, Robert, Tang, Shaojun, Schafer, Peter H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Systemic Lupus Erythematosus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279852/ https://www.ncbi.nlm.nih.gov/pubmed/35477518 http://dx.doi.org/10.1136/annrheumdis-2022-222212

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