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Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice

PURPOSE: Scleral hypoxia is a key factor that induces hypoxia-inducible factor-1α (HIF-1α) upregulation, and this response contributes to myopia progression. Currently, we aim to determine if the different HIF subtypes, including HIF-1α and HIF-2α, mediate hypoxia-induced myopia development through...

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Detalles Bibliográficos
Autores principales:	Wu, Wenjing, Su, Yongchao, Hu, Changxi, Tao, Huixin, Jiang, Ying, Zhu, Guandong, Zhu, Jiadi, Zhai, Ying, Qu, Jia, Zhou, Xiangtian, Zhao, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279925/ https://www.ncbi.nlm.nih.gov/pubmed/35802383 http://dx.doi.org/10.1167/iovs.63.8.2

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