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Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase

In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. Although TDO has been associated with cancer stemness, its involvement in melanoma stem cell biology remains largely unknown. Since we showed that...

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Detalles Bibliográficos
Autores principales: Cecchi, Marta, Mannini, Antonella, Lapucci, Andrea, Silvano, Angela, Lulli, Matteo, Luceri, Cristina, D’Ambrosio, Mario, Chiarugi, Alberto, Eid, Ali H., Parenti, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280025/
https://www.ncbi.nlm.nih.gov/pubmed/35847038
http://dx.doi.org/10.3389/fphar.2022.911019