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Pemafibrate Prevents Rupture of Angiotensin II-Induced Abdominal Aortic Aneurysms

BACKGROUND: Abdominal aortic aneurysm (AAA) is a life-threatening disease that lacks effective preventive therapies. This study aimed to evaluate the effect of pemafibrate, a selective peroxisome proliferator-activated receptor alpha (PPARα) agonist, on AAA formation and rupture. METHODS: Experiment...

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Detalles Bibliográficos
Autores principales: Amioka, Naofumi, Miyoshi, Toru, Yonezawa, Tomoko, Kondo, Megumi, Akagi, Satoshi, Yoshida, Masashi, Saito, Yukihiro, Nakamura, Kazufumi, Ito, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280056/
https://www.ncbi.nlm.nih.gov/pubmed/35845076
http://dx.doi.org/10.3389/fcvm.2022.904215

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