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Pemafibrate Prevents Rupture of Angiotensin II-Induced Abdominal Aortic Aneurysms
BACKGROUND: Abdominal aortic aneurysm (AAA) is a life-threatening disease that lacks effective preventive therapies. This study aimed to evaluate the effect of pemafibrate, a selective peroxisome proliferator-activated receptor alpha (PPARα) agonist, on AAA formation and rupture. METHODS: Experiment...
Autores principales: | Amioka, Naofumi, Miyoshi, Toru, Yonezawa, Tomoko, Kondo, Megumi, Akagi, Satoshi, Yoshida, Masashi, Saito, Yukihiro, Nakamura, Kazufumi, Ito, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280056/ https://www.ncbi.nlm.nih.gov/pubmed/35845076 http://dx.doi.org/10.3389/fcvm.2022.904215 |
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