The Anti-Histamine Azelastine, Identified by Computational Drug Repurposing, Inhibits Infection by Major Variants of SARS-CoV-2 in Cell Cultures and Reconstituted Human Nasal Tissue

Background and purpose: The COVID-19 pandemic continues to pose challenges, especially with the emergence of new SARS-CoV-2 variants that are associated with higher infectivity and/or compromised protection afforded by the current vaccines. There is a high demand for additional preventive and therap...

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Detalles Bibliográficos
Autores principales: Konrat, Robert, Papp, Henrietta, Kimpel, Janine, Rössler, Annika, Szijártó, Valéria, Nagy, Gábor, Madai, Mónika, Zeghbib, Safia, Kuczmog, Anett, Lanszki, Zsófia, Gesell, Tanja, Helyes, Zsuzsanna, Kemenesi, Gábor, Jakab, Ferenc, Nagy, Eszter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280057/
https://www.ncbi.nlm.nih.gov/pubmed/35846988
http://dx.doi.org/10.3389/fphar.2022.861295

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