IL-24 intrinsically regulates Th17 cell pathogenicity in mice

In certain instances, Th17 responses are associated with severe immunopathology. T cell–intrinsic mechanisms that restrict pathogenic effector functions have been described for type 1 and 2 responses but are less well studied for Th17 cells. Here, we report a cell-intrinsic feedback mechanism that c...

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Detalles Bibliográficos
Autores principales: Sie, Christopher, Kant, Ravi, Peter, Christian, Muschaweckh, Andreas, Pfaller, Monika, Nirschl, Lucy, Moreno, Helena Domínguez, Chadimová, Tereza, Lepennetier, Gildas, Kuhlmann, Tanja, Öllinger, Rupert, Engleitner, Thomas, Rad, Roland, Korn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280194/
https://www.ncbi.nlm.nih.gov/pubmed/35819408
http://dx.doi.org/10.1084/jem.20212443

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