Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting

The prevalence and clinical relevance of human herpesvirus-6 (HHV-6) detection in cerebrospinal fluid (CSF) using multiplex polymerase chain reaction (PCR) testing in patients with suspected meningoencephalitis in high human immunodeficiency virus-prevalence African settings are not known. We descri...

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Autores principales: Milburn, James, Lechiile, Kwana, Siamisang, Keatlaretse, Williams, Christopher G, Owen, Leah, Gwakuba, Ezekiel, Machiya, Tichaona, Leeme, Tshepo, Barton, Hannah E, Doyle, Ronan, Tenforde, Mark W, Mine, Madisa, Goldfarb, David M, Mokomane, Margaret, Jarvis, Joseph N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280324/
https://www.ncbi.nlm.nih.gov/pubmed/35854999
http://dx.doi.org/10.1093/ofid/ofac229
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author Milburn, James
Lechiile, Kwana
Siamisang, Keatlaretse
Williams, Christopher G
Owen, Leah
Gwakuba, Ezekiel
Machiya, Tichaona
Leeme, Tshepo
Barton, Hannah E
Doyle, Ronan
Tenforde, Mark W
Mine, Madisa
Goldfarb, David M
Mokomane, Margaret
Jarvis, Joseph N
author_facet Milburn, James
Lechiile, Kwana
Siamisang, Keatlaretse
Williams, Christopher G
Owen, Leah
Gwakuba, Ezekiel
Machiya, Tichaona
Leeme, Tshepo
Barton, Hannah E
Doyle, Ronan
Tenforde, Mark W
Mine, Madisa
Goldfarb, David M
Mokomane, Margaret
Jarvis, Joseph N
author_sort Milburn, James
collection PubMed
description The prevalence and clinical relevance of human herpesvirus-6 (HHV-6) detection in cerebrospinal fluid (CSF) using multiplex polymerase chain reaction (PCR) testing in patients with suspected meningoencephalitis in high human immunodeficiency virus-prevalence African settings are not known. We describe the clinical and laboratory characteristics of 13 patients with HHV-6 CSF PCR positivity in Botswana.
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spelling pubmed-92803242022-07-18 Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting Milburn, James Lechiile, Kwana Siamisang, Keatlaretse Williams, Christopher G Owen, Leah Gwakuba, Ezekiel Machiya, Tichaona Leeme, Tshepo Barton, Hannah E Doyle, Ronan Tenforde, Mark W Mine, Madisa Goldfarb, David M Mokomane, Margaret Jarvis, Joseph N Open Forum Infect Dis Brief Report The prevalence and clinical relevance of human herpesvirus-6 (HHV-6) detection in cerebrospinal fluid (CSF) using multiplex polymerase chain reaction (PCR) testing in patients with suspected meningoencephalitis in high human immunodeficiency virus-prevalence African settings are not known. We describe the clinical and laboratory characteristics of 13 patients with HHV-6 CSF PCR positivity in Botswana. Oxford University Press 2022-05-17 /pmc/articles/PMC9280324/ /pubmed/35854999 http://dx.doi.org/10.1093/ofid/ofac229 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Milburn, James
Lechiile, Kwana
Siamisang, Keatlaretse
Williams, Christopher G
Owen, Leah
Gwakuba, Ezekiel
Machiya, Tichaona
Leeme, Tshepo
Barton, Hannah E
Doyle, Ronan
Tenforde, Mark W
Mine, Madisa
Goldfarb, David M
Mokomane, Margaret
Jarvis, Joseph N
Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting
title Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting
title_full Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting
title_fullStr Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting
title_full_unstemmed Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting
title_short Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting
title_sort human herpesvirus-6 detection in cerebrospinal fluid on the biofire filmarray meningitis/encephalitis panel in a high human immunodeficiency virus-prevalence african setting
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280324/
https://www.ncbi.nlm.nih.gov/pubmed/35854999
http://dx.doi.org/10.1093/ofid/ofac229
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