Cargando…

Anti-colon Cancer Effects of Dendrobium officinale Kimura & Migo Revealed by Network Pharmacology Integrated With Molecular Docking and Metabolomics Studies

OBJECTIVE: The present study aimed to investigate the potential mechanism of Dendrobium officinale (D. officinale) on colorectal cancer and the relevant targets in the pathway using a network pharmacological approach. METHODS: (1) We identified the major bioactive components of D. officinale by UPLC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tao, Shengchang, Li, Jinyan, Wang, Huan, Ding, Shaobo, Han, Weichao, He, Ruirong, Ren, Zhiyao, Wei, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280342/ https://www.ncbi.nlm.nih.gov/pubmed/35847793 http://dx.doi.org/10.3389/fmed.2022.879986

Ejemplares similares

Traditional Uses, Phytochemistry, Pharmacology, and Quality Control of Dendrobium officinale Kimura et. Migo
por: Chen, Wenhua, et al.
Publicado: (2021)

Dendrobium officinale Kimura et Migo: A Review on Its Ethnopharmacology, Phytochemistry, Pharmacology, and Industrialization
por: Tang, Hanxiao, et al.
Publicado: (2017)

Effects of Different Molecular Weight Polysaccharides From Dendrobium officinale Kimura & Migo on Human Colorectal Cancer and Transcriptome Analysis of Differentially Expressed Genes
por: Tao, Shengchang, et al.
Publicado: (2021)

Metabolomics-Based Analysis of the Effects of Different Cultivation Strategies on Metabolites of Dendrobium officinale Kimura et Migo
por: Yang, Da, et al.
Publicado: (2023)

Dendrobium Officinale Kimura et Migo Ameliorates Insulin Resistance in Rats with Diabetic Nephropathy
por: Zhao, Ming, et al.
Publicado: (2018)

Comparison of the Antioxidant Activities and Polysaccharide Characterization of Fresh and Dry Dendrobium officinale Kimura et Migo
por: Zhang, Wang, et al.
Publicado: (2022)

Extensive Metabolic Profiles of Leaves and Stems from the Medicinal Plant Dendrobium officinale Kimura et Migo
por: Cao, Hua, et al.
Publicado: (2019)

Development, Identification, and Application of a Germplasm Specific SCAR Marker for Dendrobium officinale Kimura et Migo
por: Zheng, Kaixin, et al.
Publicado: (2021)

Genomic Characterization and Expression Analysis of the SnRK Family Genes in Dendrobium officinale Kimura et Migo (Orchidaceae)
por: Wang, Yue, et al.
Publicado: (2021)

An NMR-Based Metabolomic Approach to Unravel the Preventive Effect of Water-Soluble Extract from Dendrobium officinale Kimura & Migo on Streptozotocin-Induced Diabetes in Mice
por: Zheng, Hong, et al.
Publicado: (2017)

Comparative metabolomic analyses of Dendrobium officinale Kimura et Migo responding to UV-B radiation reveal variations in the metabolisms associated with its bioactive ingredients
por: Chen, Yue, et al.
Publicado: (2020)

Whole-Transcriptome Selection and Evaluation of Internal Reference Genes for Expression Analysis in Protocorm Development of Dendrobium officinale Kimura et Migo
por: An, Hongqiang, et al.
Publicado: (2016)

Traditional processing increases biological activities of Dendrobium offificinale Kimura et. Migo in Southeast Yunnan, China
por: Zhou, Di, et al.
Publicado: (2022)

Polysaccharides of Dendrobium officinale Kimura & Migo Leaves Protect Against Ethanol-Induced Gastric Mucosal Injury via the AMPK/mTOR Signaling Pathway in Vitro and vivo
por: Ke, Yang, et al.
Publicado: (2020)

Corrigendum: Polysaccharides of Dendrobium officinale Kimura & Migo leaves protect against ethanol-induced gastric mucosal injury via the AMPK/mTOR signaling pathway in vitro and vivo
por: Ke, Yang, et al.
Publicado: (2022)

Author Correction: Traditional processing increases biological activities of Dendrobium offificinale Kimura et. Migo in Southeast Yunnan, China
por: Zhou, Di, et al.
Publicado: (2023)

Integrated Analysis of Metabolomics Combined with Network Pharmacology and Molecular Docking Reveals the Effects of Processing on Metabolites of Dendrobium officinale
por: Xu, Lilan, et al.
Publicado: (2023)

Does the Metabolome of Wild-like Dendrobium officinale of Different Origins Have Regional Differences?
por: Lan, Qiqian, et al.
Publicado: (2022)

Structural Characterization of Polysaccharides from Dendrobium officinale and Their Effects on Apoptosis of HeLa Cell Line
por: Yu, Wenxia, et al.
Publicado: (2018)

Purification, Characterization and Biological Activity of Polysaccharides from Dendrobium officinale
por: Huang, Kaiwei, et al.
Publicado: (2016)

Comparative Metabolomic Analysis of Dendrobium officinale under Different Cultivation Substrates
por: Zuo, Si-Min, et al.
Publicado: (2020)

Network Analysis of Transcriptome and LC-MS Reveals a Possible Biosynthesis Pathway of Anthocyanins in Dendrobium officinale
por: Ren, Zhiyao, et al.
Publicado: (2020)

HPLC-based metabolomics of Dendrobium officinale revealing its antioxidant ability
por: Luo, Zhengfei, et al.
Publicado: (2023)

Simultaneous identification and determination of flavonoids in Dendrobium officinale
por: Zhou, Chunhua, et al.
Publicado: (2018)

Metabolomic and transcriptomic analyses reveal the regulation of pigmentation in the purple variety of Dendrobium officinale
por: Zhan, Xinqiao, et al.
Publicado: (2020)

Hypoglycemic effects of dendrobium officinale leaves
por: Lv, Ming, et al.
Publicado: (2023)

Transcriptome and Metabolome Reveal Salt-Stress Responses of Leaf Tissues from Dendrobium officinale
por: Zhang, Mingze, et al.
Publicado: (2021)

Light and Potassium Improve the Quality of Dendrobium officinale through Optimizing Transcriptomic and Metabolomic Alteration
por: Jia, Yue, et al.
Publicado: (2022)

The Mechanism of Dendrobium officinale as a Treatment for Hyperlipidemia Based on Network Pharmacology and Experimental Validation
por: Li, Lin-Zi, et al.
Publicado: (2022)

Network Pharmacologic Analysis of Dendrobium officinale Extract Inhibiting the Proliferation of Gastric Cancer Cells
por: Wei, Lianping, et al.
Publicado: (2022)

Phytochemical profiles of edible flowers of medicinal plants of Dendrobium officinale and Dendrobium devonianum
por: Zhao, Ming, et al.
Publicado: (2021)

Dendrobium officinale Endophytes May Colonize the Intestinal Tract and Regulate Gut Microbiota in Mice
por: Chen, Wenhua, et al.
Publicado: (2022)

Metabolic Analysis of Medicinal Dendrobium officinale and Dendrobium huoshanense during Different Growth Years
por: Jin, Qing, et al.
Publicado: (2016)

Molecular Identification of Endophytic Fungi and Their Pathogenicity Evaluation Against Dendrobium nobile and Dendrobium officinale
por: Sarsaiya, Surendra, et al.
Publicado: (2020)

Effect of Dendrobium officinale Extraction on Gastric Carcinogenesis in Rats
por: Zhao, Yi, et al.
Publicado: (2016)

Characterization and Control of Dendrobium officinale Bud Blight Disease
por: Zhang, Jinzhao, et al.
Publicado: (2023)

Chemical Differentiation of Dendrobium officinale and Dendrobium devonianum by Using HPLC Fingerprints, HPLC-ESI-MS, and HPTLC Analyses
por: Ye, Zi, et al.
Publicado: (2017)

Insights from the Cold Transcriptome and Metabolome of Dendrobium officinale: Global Reprogramming of Metabolic and Gene Regulation Networks during Cold Acclimation
por: Wu, Zhi-Gang, et al.
Publicado: (2016)

Metabolic Profiling of Dendrobium officinale in Response to Precursors and Methyl Jasmonate
por: Jiao, Chunyan, et al.
Publicado: (2018)

Quality Markers of Dendrobium officinale by “Oligosaccharide-Spectrum-Effect” Relationships
por: Liu, Ruimin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sv0jqvr6jqss3rm4sclsi4f8om