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Multifocal and pathologically-confirmed brain metastasis complete response to trastuzumab deruxtecan

Antibody–drug conjugates have transformed the treatment of HER2+ breast and other cancers. Unfortunately, the CNS remains a sanctuary site for many such patients in part due to poor macromolecule penetration across the blood–brain tumor barrier. Trastuzumab deruxtecan (T-DXd), a high-payload antibod...

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Detalles Bibliográficos
Autores principales:	Moss, Nelson S, Tosi, Umberto, Santomasso, Bianca D, Beal, Kathryn, Modi, Shanu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Medicine Ltd 2022
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280405/ https://www.ncbi.nlm.nih.gov/pubmed/35674041 http://dx.doi.org/10.2217/cns-2022-0010

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