Naltrexone-Induced Cardiac Function Improvement is Associated With an Attenuated Inflammatory Response and Lipid Perioxidation in Volume Overloaded Rats

In previous studies, upregulation of myocardial opioid receptors as well as the precursors of their endogenous ligands were detected in the failing heart due to chronic volume overload. Moreover, opioid receptor blockade by naltrexone improved left ventricular function. In parallel, inflammatory pro...

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Detalles Bibliográficos
Autores principales: Dehe, Lukas, Mousa, Shaaban A., Shaqura, Mohammed, Shakibaei, Mehdi, Schäfer, Michael, Treskatsch, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280420/
https://www.ncbi.nlm.nih.gov/pubmed/35847039
http://dx.doi.org/10.3389/fphar.2022.873169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280420/
https://www.ncbi.nlm.nih.gov/pubmed/35847039
http://dx.doi.org/10.3389/fphar.2022.873169

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