A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine

This is a case report of a 31-year-old lady who is known to have ulcerative colitis for 15 years and was on mesalazine. She presented with periorbital swelling, sinusitis, epistaxis, and was found to have positive anti-neutrophil cytoplasmic antibody and anti-proteinase-3 of a high titer. Biopsy fro...

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Autores principales: Alokaily, Fahdah, AlKathiri, Reem, AlKathiri, Sarah, Alrashidi, Seham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Saudi Medical Journal 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280563/
https://www.ncbi.nlm.nih.gov/pubmed/35022291
http://dx.doi.org/10.15537/smj.2022.43.1.20210914
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author Alokaily, Fahdah
AlKathiri, Reem
AlKathiri, Sarah
Alrashidi, Seham
author_facet Alokaily, Fahdah
AlKathiri, Reem
AlKathiri, Sarah
Alrashidi, Seham
author_sort Alokaily, Fahdah
collection PubMed
description This is a case report of a 31-year-old lady who is known to have ulcerative colitis for 15 years and was on mesalazine. She presented with periorbital swelling, sinusitis, epistaxis, and was found to have positive anti-neutrophil cytoplasmic antibody and anti-proteinase-3 of a high titer. Biopsy from the maxillary sinus showed chronic non-specific inflammation and biopsy from the periorbital fat revealed inflammation and granulomatous changes. She had no other organ involvement. She was diagnosed with a limited form of granumatosis and polyangiitis and treated with methotrexate and prednisolone. The symptoms disappeared after treatment.
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spelling pubmed-92805632022-07-20 A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine Alokaily, Fahdah AlKathiri, Reem AlKathiri, Sarah Alrashidi, Seham Saudi Med J Case Report This is a case report of a 31-year-old lady who is known to have ulcerative colitis for 15 years and was on mesalazine. She presented with periorbital swelling, sinusitis, epistaxis, and was found to have positive anti-neutrophil cytoplasmic antibody and anti-proteinase-3 of a high titer. Biopsy from the maxillary sinus showed chronic non-specific inflammation and biopsy from the periorbital fat revealed inflammation and granulomatous changes. She had no other organ involvement. She was diagnosed with a limited form of granumatosis and polyangiitis and treated with methotrexate and prednisolone. The symptoms disappeared after treatment. Saudi Medical Journal 2022-01 /pmc/articles/PMC9280563/ /pubmed/35022291 http://dx.doi.org/10.15537/smj.2022.43.1.20210914 Text en Copyright: © Saudi Medical Journal https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.
spellingShingle Case Report
Alokaily, Fahdah
AlKathiri, Reem
AlKathiri, Sarah
Alrashidi, Seham
A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine
title A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine
title_full A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine
title_fullStr A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine
title_full_unstemmed A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine
title_short A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine
title_sort limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280563/
https://www.ncbi.nlm.nih.gov/pubmed/35022291
http://dx.doi.org/10.15537/smj.2022.43.1.20210914
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