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Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis

COVID vaccinations have been an important step in controlling the COVID-19 pandemic. Despite the fact they were generally safe and effective, a few case reports of renal disorders have been published following COVID vaccines. We report a 29-year-old man with history of Chronic Kidney Disease who pre...

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Detalles Bibliográficos
Autores principales: Al Bakr, Saad, Alaithan, Mufaddal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Saudi Medical Journal 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280603/
https://www.ncbi.nlm.nih.gov/pubmed/35537721
http://dx.doi.org/10.15537/smj.2022.43.5.20220139
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author Al Bakr, Saad
Alaithan, Mufaddal A.
author_facet Al Bakr, Saad
Alaithan, Mufaddal A.
author_sort Al Bakr, Saad
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description COVID vaccinations have been an important step in controlling the COVID-19 pandemic. Despite the fact they were generally safe and effective, a few case reports of renal disorders have been published following COVID vaccines. We report a 29-year-old man with history of Chronic Kidney Disease who presented to our center with flank pain after receiving AstraZeneca COVID vaccine. He also had history of raw milk ingestion. His initial investigations showed high creatinine with high level of proteinuria. A renal biopsy was consistent with immune complex-mediated glomerulonephritis on top of renal fibrosis. His brucella serology also showed high titer. He was started on treatment for Brucellosis and planned for follow-up afterwards for further therapy. To the best of our knowledge, this is the first reported case of concomitant Brucellosis and post COVID vaccine glomerulonephritis.
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spelling pubmed-92806032022-07-22 Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis Al Bakr, Saad Alaithan, Mufaddal A. Saudi Med J Case Report COVID vaccinations have been an important step in controlling the COVID-19 pandemic. Despite the fact they were generally safe and effective, a few case reports of renal disorders have been published following COVID vaccines. We report a 29-year-old man with history of Chronic Kidney Disease who presented to our center with flank pain after receiving AstraZeneca COVID vaccine. He also had history of raw milk ingestion. His initial investigations showed high creatinine with high level of proteinuria. A renal biopsy was consistent with immune complex-mediated glomerulonephritis on top of renal fibrosis. His brucella serology also showed high titer. He was started on treatment for Brucellosis and planned for follow-up afterwards for further therapy. To the best of our knowledge, this is the first reported case of concomitant Brucellosis and post COVID vaccine glomerulonephritis. Saudi Medical Journal 2022-05 /pmc/articles/PMC9280603/ /pubmed/35537721 http://dx.doi.org/10.15537/smj.2022.43.5.20220139 Text en Copyright: © Saudi Medical Journal https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.
spellingShingle Case Report
Al Bakr, Saad
Alaithan, Mufaddal A.
Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis
title Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis
title_full Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis
title_fullStr Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis
title_full_unstemmed Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis
title_short Immune complex-mediated glomerulonephritis post COVID-19 vaccination in a patient with concomitant Brucellosis
title_sort immune complex-mediated glomerulonephritis post covid-19 vaccination in a patient with concomitant brucellosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280603/
https://www.ncbi.nlm.nih.gov/pubmed/35537721
http://dx.doi.org/10.15537/smj.2022.43.5.20220139
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