Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma

[Image: see text] Despite advances in proteomic technologies, clinical translation of plasma biomarkers remains low, partly due to a major bottleneck between the discovery of candidate biomarkers and costly clinical validation studies. Due to a dearth of multiplexable assays, generally only a few ca...

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Detalles Bibliográficos
Autores principales: Kennedy, Jacob J., Whiteaker, Jeffrey R., Ivey, Richard G., Burian, Aura, Chowdhury, Shrabanti, Tsai, Chia-Feng, Liu, Tao, Lin, ChenWei, Murillo, Oscar D., Lundeen, Rachel A., Jones, Lisa A., Gafken, Philip R., Longton, Gary, Rodland, Karin D., Skates, Steven J., Landua, John, Wang, Pei, Lewis, Michael T., Paulovich, Amanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280723/
https://www.ncbi.nlm.nih.gov/pubmed/35767427
http://dx.doi.org/10.1021/acs.analchem.1c04382

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