Cargando…

Discrete-Time Modeling of COVID-19 Propagation in Argentina with Explicit Delays

We present a new deterministic discrete-time compartmental model of COVID-19 that explicitly takes into account relevant delays related to the stages of the disease, its diagnosis and report system, allowing to represent the presence of imported cases. In addition to developing the model equations,...

Descripción completa

Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IEEE 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280810/
https://www.ncbi.nlm.nih.gov/pubmed/35939270
http://dx.doi.org/10.1109/MCSE.2020.3040700
_version_ 1784746733869203456
collection PubMed
description We present a new deterministic discrete-time compartmental model of COVID-19 that explicitly takes into account relevant delays related to the stages of the disease, its diagnosis and report system, allowing to represent the presence of imported cases. In addition to developing the model equations, we describe an automatic parameter fitting mechanism using official data on the spread of the virus in Argentina. The result consistently reflects the behavior of the disease with respect to characteristic times: latency, infectious period, report of cases (confirmed and dead), and allows for detecting automatically changes in the reproductive number and in the mortality factor. We also analyse the model's prediction capability and present simulation results assuming different future scenarios. We discuss usage of the model in a closed-loop control scheme, where the explicit presence of delays plays a key role in projecting more realistic dynamics than that of classic continuous-time models.
format Online
Article
Text
id pubmed-9280810
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher IEEE
record_format MEDLINE/PubMed
spelling pubmed-92808102022-08-01 Discrete-Time Modeling of COVID-19 Propagation in Argentina with Explicit Delays Comput Sci Eng Theme Article: Computational Science in the Fight against Covid-19, Part II We present a new deterministic discrete-time compartmental model of COVID-19 that explicitly takes into account relevant delays related to the stages of the disease, its diagnosis and report system, allowing to represent the presence of imported cases. In addition to developing the model equations, we describe an automatic parameter fitting mechanism using official data on the spread of the virus in Argentina. The result consistently reflects the behavior of the disease with respect to characteristic times: latency, infectious period, report of cases (confirmed and dead), and allows for detecting automatically changes in the reproductive number and in the mortality factor. We also analyse the model's prediction capability and present simulation results assuming different future scenarios. We discuss usage of the model in a closed-loop control scheme, where the explicit presence of delays plays a key role in projecting more realistic dynamics than that of classic continuous-time models. IEEE 2020-11-27 /pmc/articles/PMC9280810/ /pubmed/35939270 http://dx.doi.org/10.1109/MCSE.2020.3040700 Text en This article is free to access and download, along with rights for full text and data mining, re-use and analysis.
spellingShingle Theme Article: Computational Science in the Fight against Covid-19, Part II
Discrete-Time Modeling of COVID-19 Propagation in Argentina with Explicit Delays
title Discrete-Time Modeling of COVID-19 Propagation in Argentina with Explicit Delays
title_full Discrete-Time Modeling of COVID-19 Propagation in Argentina with Explicit Delays
title_fullStr Discrete-Time Modeling of COVID-19 Propagation in Argentina with Explicit Delays
title_full_unstemmed Discrete-Time Modeling of COVID-19 Propagation in Argentina with Explicit Delays
title_short Discrete-Time Modeling of COVID-19 Propagation in Argentina with Explicit Delays
title_sort discrete-time modeling of covid-19 propagation in argentina with explicit delays
topic Theme Article: Computational Science in the Fight against Covid-19, Part II
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280810/
https://www.ncbi.nlm.nih.gov/pubmed/35939270
http://dx.doi.org/10.1109/MCSE.2020.3040700
work_keys_str_mv AT discretetimemodelingofcovid19propagationinargentinawithexplicitdelays
AT discretetimemodelingofcovid19propagationinargentinawithexplicitdelays
AT discretetimemodelingofcovid19propagationinargentinawithexplicitdelays
AT discretetimemodelingofcovid19propagationinargentinawithexplicitdelays