Associations of β-Amyloid and Vascular Burden With Rates of Neurodegeneration in Cognitively Normal Members of the 1946 British Birth Cohort

BACKGROUND AND OBJECTIVES: The goals of this work were to quantify the independent and interactive associations of β-amyloid (Aβ) and white matter hyperintensity volume (WMHV), a marker of presumed cerebrovascular disease (CVD), with rates of neurodegeneration and to examine the contributions of APO...

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Detalles Bibliográficos
Autores principales: Keuss, Sarah E., Coath, William, Nicholas, Jennifer M., Poole, Teresa, Barnes, Josephine, Cash, David M., Lane, Christopher A., Parker, Thomas D., Keshavan, Ashvini, Buchanan, Sarah M., Wagen, Aaron Z., Storey, Mathew, Harris, Matthew, Malone, Ian B., Sudre, Carole H., Lu, Kirsty, James, Sarah-Naomi, Street, Rebecca, Thomas, David L., Dickson, John C., Murray-Smith, Heidi, Wong, Andrew, Freiberger, Tamar, Crutch, Sebastian, Richards, Marcus, Fox, Nick C., Schott, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280996/
https://www.ncbi.nlm.nih.gov/pubmed/35410910
http://dx.doi.org/10.1212/WNL.0000000000200524

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