SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma

BACKGROUND: The mechanism by which glioblastoma evades temozolomide (TMZ)-induced cytotoxicity is largely unknown. We hypothesized that mitochondria plays a role in this process. METHODS: RNA transcriptomes were obtained from tumor samples and online databases. Expression of different proteins was m...

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Detalles Bibliográficos
Autores principales: Chien, Chia-Hung, Yang, Wen-Bin, Chuang, Jian-Ying, Lee, Jung-Shun, Liao, Wei-An, Huang, Chih-Yuan, Chen, Pin-Yuan, Wu, An-Chih, Yang, Shun-Tai, Lai, Chien-Cheng, Chi, Pei-I, Chu, Jui-Mei, Cheng, Siao Muk, Liu, Chan-Chuan, Hwang, Daw-Yang, Chen, Shang-Hung, Chang, Kwang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281043/
https://www.ncbi.nlm.nih.gov/pubmed/35831908
http://dx.doi.org/10.1186/s13046-022-02429-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281043/
https://www.ncbi.nlm.nih.gov/pubmed/35831908
http://dx.doi.org/10.1186/s13046-022-02429-8

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