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Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity

Th17 cells are key drivers of autoimmune disease. However, the signaling pathways regulating Th17 polarization are poorly understood. Hedgehog signaling regulates cell fate decisions during embryogenesis and adult tissue patterning. Here we find that cell-autonomous Hedgehog signaling, independent o...

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Detalles Bibliográficos
Autores principales:	Hanna, Joachim, Beke, Flavio, O’Brien, Louise M., Kapeni, Chrysa, Chen, Hung-Chang, Carbonaro, Valentina, Kim, Alexander B., Kishore, Kamal, Adolph, Timon E., Skjoedt, Mikkel-Ole, Skjoedt, Karsten, de la Roche, Marc, de la Roche, Maike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281293/ https://www.ncbi.nlm.nih.gov/pubmed/35835905 http://dx.doi.org/10.1038/s41467-022-31722-5

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