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In Vivo Distribution and Therapeutic Efficacy of Radioiodine-Labeled pH-Low Insertion Peptide Variant 3 in a Mouse Model of Breast Cancer

PURPOSE: Extracellular acidity is a marker of highly aggressive breast cancer (BC). pH-low insertion peptides (pHLIPs) target the acidic tumor microenvironment. This study evaluates the distribution and therapeutic efficacy of radioiodine-labeled pHLIP variant 3 (Var3) in a mouse model of BC. METHOD...

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Detalles Bibliográficos
Autores principales:	Zhang, Min, Xi, Yue, Chen, Hong, Hai, Wangxi, Li, Biao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281440/ https://www.ncbi.nlm.nih.gov/pubmed/35903249 http://dx.doi.org/10.1155/2022/7456365

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