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Protein Quality Control at the Sarcomere: Titin Protection and Turnover and Implications for Disease Development
Sarcomeres are mainly composed of filament and signaling proteins and are the smallest molecular units of muscle contraction and relaxation. The sarcomere protein titin serves as a molecular spring whose stiffness mediates myofilament extensibility in skeletal and cardiac muscle. Due to the enormous...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281568/ https://www.ncbi.nlm.nih.gov/pubmed/35846001 http://dx.doi.org/10.3389/fphys.2022.914296 |