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Septins guide noncentrosomal microtubules to promote focal adhesion disassembly in migrating cells

Endothelial cell migration is critical for vascular angiogenesis and is compromised to facilitate tumor metastasis. The migratory process requires the coordinated assembly and disassembly of focal adhesions (FA), actin, and microtubules (MT). MT dynamics at FAs deliver vesicular cargoes and enhance...

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Detalles Bibliográficos
Autores principales: Merenich, Daniel, Nakos, Konstantinos, Pompan, Taylor, Donovan, Samantha J., Gill, Amrik, Patel, Pranav, Spiliotis, Elias T., Myers, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282018/
https://www.ncbi.nlm.nih.gov/pubmed/35274967
http://dx.doi.org/10.1091/mbc.E21-06-0334