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Septins guide noncentrosomal microtubules to promote focal adhesion disassembly in migrating cells
Endothelial cell migration is critical for vascular angiogenesis and is compromised to facilitate tumor metastasis. The migratory process requires the coordinated assembly and disassembly of focal adhesions (FA), actin, and microtubules (MT). MT dynamics at FAs deliver vesicular cargoes and enhance...
Autores principales: | Merenich, Daniel, Nakos, Konstantinos, Pompan, Taylor, Donovan, Samantha J., Gill, Amrik, Patel, Pranav, Spiliotis, Elias T., Myers, Kenneth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282018/ https://www.ncbi.nlm.nih.gov/pubmed/35274967 http://dx.doi.org/10.1091/mbc.E21-06-0334 |
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