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Delayed diagnosis of multiple systemic disseminated tuberculosis: A case report

RATIONALE: The clinical manifestations in patients with disseminated tuberculosis (TB) are nonspecific and may present challenges for early diagnosis. PATIENT CONCERNS AND DIAGNOSES: We describe the case of a 44-year-old man who presented with abdominal pain and discomfort for more than a month. He...

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Detalles Bibliográficos
Autores principales: Li, Huan, He, Fang, Zhong, Cejun, Qu, Junyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282118/
https://www.ncbi.nlm.nih.gov/pubmed/35363160
http://dx.doi.org/10.1097/MD.0000000000028656
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author Li, Huan
He, Fang
Zhong, Cejun
Qu, Junyan
author_facet Li, Huan
He, Fang
Zhong, Cejun
Qu, Junyan
author_sort Li, Huan
collection PubMed
description RATIONALE: The clinical manifestations in patients with disseminated tuberculosis (TB) are nonspecific and may present challenges for early diagnosis. PATIENT CONCERNS AND DIAGNOSES: We describe the case of a 44-year-old man who presented with abdominal pain and discomfort for more than a month. He had undergone surgery for a chest wall abscess 9 months ago. Computed tomography scans showed a miliary pattern in the lung and multiple abscesses in the liver, spleen, left psoas major muscle, skin, and soft tissue, with rim enhancement. Mycobacterium tuberculosis was detected in the drainage fluid of the abscesses and surgical slices, and disseminated TB was diagnosed. INTERVENTIONS AND OUTCOMES: With anti-tuberculosis therapy, the abscesses were gradually absorbed and all cultures were negative. LESSONS: The patient exemplifies the difficulty of the early diagnosis of disseminated TB. Disseminated TB should be considered first in patients with multisystem illness, and then evidence should be pursued relentlessly to establish a diagnosis.
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spelling pubmed-92821182022-08-02 Delayed diagnosis of multiple systemic disseminated tuberculosis: A case report Li, Huan He, Fang Zhong, Cejun Qu, Junyan Medicine (Baltimore) 4900 RATIONALE: The clinical manifestations in patients with disseminated tuberculosis (TB) are nonspecific and may present challenges for early diagnosis. PATIENT CONCERNS AND DIAGNOSES: We describe the case of a 44-year-old man who presented with abdominal pain and discomfort for more than a month. He had undergone surgery for a chest wall abscess 9 months ago. Computed tomography scans showed a miliary pattern in the lung and multiple abscesses in the liver, spleen, left psoas major muscle, skin, and soft tissue, with rim enhancement. Mycobacterium tuberculosis was detected in the drainage fluid of the abscesses and surgical slices, and disseminated TB was diagnosed. INTERVENTIONS AND OUTCOMES: With anti-tuberculosis therapy, the abscesses were gradually absorbed and all cultures were negative. LESSONS: The patient exemplifies the difficulty of the early diagnosis of disseminated TB. Disseminated TB should be considered first in patients with multisystem illness, and then evidence should be pursued relentlessly to establish a diagnosis. Lippincott Williams & Wilkins 2022-02-18 /pmc/articles/PMC9282118/ /pubmed/35363160 http://dx.doi.org/10.1097/MD.0000000000028656 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle 4900
Li, Huan
He, Fang
Zhong, Cejun
Qu, Junyan
Delayed diagnosis of multiple systemic disseminated tuberculosis: A case report
title Delayed diagnosis of multiple systemic disseminated tuberculosis: A case report
title_full Delayed diagnosis of multiple systemic disseminated tuberculosis: A case report
title_fullStr Delayed diagnosis of multiple systemic disseminated tuberculosis: A case report
title_full_unstemmed Delayed diagnosis of multiple systemic disseminated tuberculosis: A case report
title_short Delayed diagnosis of multiple systemic disseminated tuberculosis: A case report
title_sort delayed diagnosis of multiple systemic disseminated tuberculosis: a case report
topic 4900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282118/
https://www.ncbi.nlm.nih.gov/pubmed/35363160
http://dx.doi.org/10.1097/MD.0000000000028656
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