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Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions
Macromolecular phase separation is thought to be one of the processes that drives the formation of membraneless biomolecular condensates in cells. The dynamics of phase separation are thought to follow the tenets of classical nucleation theory, and, therefore, subsaturated solutions should be devoid...
Autores principales: | Kar, Mrityunjoy, Dar, Furqan, Welsh, Timothy J., Vogel, Laura T., Kühnemuth, Ralf, Majumdar, Anupa, Krainer, Georg, Franzmann, Titus M., Alberti, Simon, Seidel, Claus A. M., Knowles, Tuomas P. J., Hyman, Anthony A., Pappu, Rohit V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282234/ https://www.ncbi.nlm.nih.gov/pubmed/35787038 http://dx.doi.org/10.1073/pnas.2202222119 |
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