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Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions

Macromolecular phase separation is thought to be one of the processes that drives the formation of membraneless biomolecular condensates in cells. The dynamics of phase separation are thought to follow the tenets of classical nucleation theory, and, therefore, subsaturated solutions should be devoid...

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Detalles Bibliográficos
Autores principales: Kar, Mrityunjoy, Dar, Furqan, Welsh, Timothy J., Vogel, Laura T., Kühnemuth, Ralf, Majumdar, Anupa, Krainer, Georg, Franzmann, Titus M., Alberti, Simon, Seidel, Claus A. M., Knowles, Tuomas P. J., Hyman, Anthony A., Pappu, Rohit V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282234/
https://www.ncbi.nlm.nih.gov/pubmed/35787038
http://dx.doi.org/10.1073/pnas.2202222119

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