STING activation promotes robust immune response and NK cell–mediated tumor regression in glioblastoma models

Immunotherapy has had a tremendous impact on cancer treatment in the past decade, with hitherto unseen responses at advanced and metastatic stages of the disease. However, the aggressive brain tumor glioblastoma (GBM) is highly immunosuppressive and remains largely refractory to current immunotherap...

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Detalles Bibliográficos
Autores principales: Berger, Gilles, Knelson, Erik H., Jimenez-Macias, Jorge L., Nowicki, Michal O., Han, Saemi, Panagioti, Eleni, Lizotte, Patrick H., Adu-Berchie, Kwasi, Stafford, Alexander, Dimitrakakis, Nikolaos, Zhou, Lanlan, Chiocca, E. Antonio, Mooney, David J., Barbie, David A., Lawler, Sean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282249/
https://www.ncbi.nlm.nih.gov/pubmed/35787058
http://dx.doi.org/10.1073/pnas.2111003119

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