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Posttranslational modifications optimize the ability of SARS-CoV-2 spike for effective interaction with host cell receptors

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein is the prime target for vaccines, diagnostics, and therapeutic antibodies against the virus. While anchored in the viral envelope, for effective virulence, the spike needs to maintain structural flexibility to recognize...

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Detalles Bibliográficos
Autores principales: Kapoor, Karan, Chen, Tianle, Tajkhorshid, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282386/
https://www.ncbi.nlm.nih.gov/pubmed/35737823
http://dx.doi.org/10.1073/pnas.2119761119