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Posttranslational modifications optimize the ability of SARS-CoV-2 spike for effective interaction with host cell receptors
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein is the prime target for vaccines, diagnostics, and therapeutic antibodies against the virus. While anchored in the viral envelope, for effective virulence, the spike needs to maintain structural flexibility to recognize...
Autores principales: | Kapoor, Karan, Chen, Tianle, Tajkhorshid, Emad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282386/ https://www.ncbi.nlm.nih.gov/pubmed/35737823 http://dx.doi.org/10.1073/pnas.2119761119 |
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