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ATG7 is a haploinsufficient repressor of tumor progression and promoter of metastasis

The role of autophagy in cancer is complex. Both tumor-promoting and tumor-suppressive effects are reported, with tumor type, stage and specific genetic lesions dictating the role. This calls for analysis in models that best recapitulate each tumor type, from initiation to metastatic disease, to spe...

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Detalles Bibliográficos
Autores principales: Long, Jaclyn S., Kania, Elżbieta, McEwan, David G., Barthet, Valentin J. A., Brucoli, Martina, Ladds, Marcus J.G.W., Nössing, Christoph, Ryan, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282388/
https://www.ncbi.nlm.nih.gov/pubmed/35867735
http://dx.doi.org/10.1073/pnas.2113465119