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Histologically resolved multiomics enables precise molecular profiling of human intratumor heterogeneity
Both the composition of cell types and their spatial distribution in a tissue play a critical role in cellular function, organ development, and disease progression. For example, intratumor heterogeneity and the distribution of transcriptional and genetic events in single cells drive the genesis and...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282480/ https://www.ncbi.nlm.nih.gov/pubmed/35776767 http://dx.doi.org/10.1371/journal.pbio.3001699 |