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Enrichment of circulating trophoblasts from maternal blood using filtration-based Metacell® technology

In a cell-based non-invasive prenatal test (cbNIPT), intact circulating trophoblasts (CTs) are isolated from maternal blood for subsequent genetic analysis. Enrichment of these CTs from maternal blood is the most challenging step in the cbNIPT workflow. This study aims to assess the suitability of t...

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Detalles Bibliográficos
Autores principales:	Weymaere, Jana, Vander Plaetsen, Ann-Sophie, Van Den Branden, Yasmine, Pospisilova, Eliska, Tytgat, Olivier, Deforce, Dieter, Van Nieuwerburgh, Filip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282611/ https://www.ncbi.nlm.nih.gov/pubmed/35834570 http://dx.doi.org/10.1371/journal.pone.0271226

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