A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer

[Image: see text] Kallikrein-related peptidases (KLKs) are a family of secreted serine proteases, which form a network (the KLK activome) with an important role in proteolysis and signaling. In prostate cancer (PCa), increased KLK activity promotes tumor growth and metastasis through multiple bioche...

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Detalles Bibliográficos
Autores principales: Lovell, Scott, Zhang, Leran, Kryza, Thomas, Neodo, Anna, Bock, Nathalie, De Vita, Elena, Williams, Elizabeth D., Engelsberger, Elisabeth, Xu, Congyi, Bakker, Alexander T., Maneiro, Maria, Tanaka, Reiko J., Bevan, Charlotte L., Clements, Judith A., Tate, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282638/
https://www.ncbi.nlm.nih.gov/pubmed/34085829
http://dx.doi.org/10.1021/jacs.1c03950

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