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Therapeutic induction of Bcl2‐associated athanogene 3‐mediated autophagy in idiopathic pulmonary fibrosis

BACKGROUND: Exaggerated fibroblast proliferation is a well‐known feature in idiopathic pulmonary fibrosis (IPF) which may be – in part – due to insufficient autophagy, a lysosome dependent cellular surveillance pathway. Bcl2‐associated athanogene 3 (BAG3) is a pivotal co‐chaperone of the autophagy p...

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Detalles Bibliográficos
Autores principales: Chillappagari, Shashipavan, Schwarz, Julian, Kesireddy, Vidyasagar, Knoell, Jessica, Korfei, Martina, Hoetzenecker, Konrad, Schmitz, M. Lienhard, Behl, Christian, Bellusci, Saverio, Guenther, Andreas, Mahavadi, Poornima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282656/
https://www.ncbi.nlm.nih.gov/pubmed/35834635
http://dx.doi.org/10.1002/ctm2.935

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