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Local hyperexcitability of C-nociceptors may predict responsiveness to topical lidocaine in neuropathic pain

We explored whether increased C-nociceptor excitability predicts analgesic effects of topical lidocaine in 33 patients with mono- (n = 15) or poly-neuropathy (n = 18). Excitability of C-nociceptors was tested by transcutaneous electrical sinusoidal (4 Hz) and half sine wave (single 500 ms pulse) sti...

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Detalles Bibliográficos
Autores principales:	Landmann, Gunther, Stockinger, Lenka, Gerber, Benjamin, Benrath, Justus, Schmelz, Martin, Rukwied, Roman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282664/ https://www.ncbi.nlm.nih.gov/pubmed/35834539 http://dx.doi.org/10.1371/journal.pone.0271327

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