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Investigation of D76N β(2)-Microglobulin Using Protein Footprinting and Structural Mass Spectrometry

[Image: see text] NMR studies and X-ray crystallography have shown that the structures of the 99-residue amyloidogenic protein β(2)-microglobulin (β(2)m) and its more aggregation-prone variant, D76N, are indistinguishable, and hence, the reason for the striking difference in their aggregation propen...

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Detalles Bibliográficos
Autores principales:	Cornwell, Owen, Ault, James R., Bond, Nicholas J., Radford, Sheena E., Ashcroft, Alison E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282677/ https://www.ncbi.nlm.nih.gov/pubmed/33586970 http://dx.doi.org/10.1021/jasms.0c00438

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