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A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India

INTRODUCTION: Lichen sclerosus (LS) is a chronic dermatosis frequently located over labial, perineal, and perianal areas. The etiology is multifactorial and includes genetic, autoimmune, hormonal, and infectious aspects. MATERIALS AND METHODS: A series of twenty genital LS patients was carried out t...

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Detalles Bibliográficos
Autores principales: Brar, Sukhmani Kaur, Bano, Rubeena, Puri, Neerja, Singh, Amarbir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282700/
https://www.ncbi.nlm.nih.gov/pubmed/35846549
http://dx.doi.org/10.4103/ijstd.ijstd_126_20
Descripción
Sumario:INTRODUCTION: Lichen sclerosus (LS) is a chronic dermatosis frequently located over labial, perineal, and perianal areas. The etiology is multifactorial and includes genetic, autoimmune, hormonal, and infectious aspects. MATERIALS AND METHODS: A series of twenty genital LS patients was carried out to evaluate the signs, symptoms, complications, and affliction of quality of life. RESULTS: Eighteen out of twenty patients were female between 30 and 73 years and showed smooth, glistening, and whitish plaques. The mean duration was 8.4 years. Itching and burning was the most common symptom (75%) corresponding to excoriation and fissuring of genitalia (75%). Malignancy was seen in two cases (10%). The mean Vulvar Quality of Life Index was 9.2, higher in younger patients. DISCUSSION: LS is a disorder of older age group with female preponderance. It is a source of significant morbidity, and long-standing cases predispose to vulvar malignancy. CONCLUSION: To conclude, early diagnosis with proper counselling of the patient and his/her partner regarding various aspects of disease are essential for a wholesome approach.