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A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India
INTRODUCTION: Lichen sclerosus (LS) is a chronic dermatosis frequently located over labial, perineal, and perianal areas. The etiology is multifactorial and includes genetic, autoimmune, hormonal, and infectious aspects. MATERIALS AND METHODS: A series of twenty genital LS patients was carried out t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282700/ https://www.ncbi.nlm.nih.gov/pubmed/35846549 http://dx.doi.org/10.4103/ijstd.ijstd_126_20 |
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author | Brar, Sukhmani Kaur Bano, Rubeena Puri, Neerja Singh, Amarbir |
author_facet | Brar, Sukhmani Kaur Bano, Rubeena Puri, Neerja Singh, Amarbir |
author_sort | Brar, Sukhmani Kaur |
collection | PubMed |
description | INTRODUCTION: Lichen sclerosus (LS) is a chronic dermatosis frequently located over labial, perineal, and perianal areas. The etiology is multifactorial and includes genetic, autoimmune, hormonal, and infectious aspects. MATERIALS AND METHODS: A series of twenty genital LS patients was carried out to evaluate the signs, symptoms, complications, and affliction of quality of life. RESULTS: Eighteen out of twenty patients were female between 30 and 73 years and showed smooth, glistening, and whitish plaques. The mean duration was 8.4 years. Itching and burning was the most common symptom (75%) corresponding to excoriation and fissuring of genitalia (75%). Malignancy was seen in two cases (10%). The mean Vulvar Quality of Life Index was 9.2, higher in younger patients. DISCUSSION: LS is a disorder of older age group with female preponderance. It is a source of significant morbidity, and long-standing cases predispose to vulvar malignancy. CONCLUSION: To conclude, early diagnosis with proper counselling of the patient and his/her partner regarding various aspects of disease are essential for a wholesome approach. |
format | Online Article Text |
id | pubmed-9282700 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-92827002022-07-15 A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India Brar, Sukhmani Kaur Bano, Rubeena Puri, Neerja Singh, Amarbir Indian J Sex Transm Dis AIDS Original Article INTRODUCTION: Lichen sclerosus (LS) is a chronic dermatosis frequently located over labial, perineal, and perianal areas. The etiology is multifactorial and includes genetic, autoimmune, hormonal, and infectious aspects. MATERIALS AND METHODS: A series of twenty genital LS patients was carried out to evaluate the signs, symptoms, complications, and affliction of quality of life. RESULTS: Eighteen out of twenty patients were female between 30 and 73 years and showed smooth, glistening, and whitish plaques. The mean duration was 8.4 years. Itching and burning was the most common symptom (75%) corresponding to excoriation and fissuring of genitalia (75%). Malignancy was seen in two cases (10%). The mean Vulvar Quality of Life Index was 9.2, higher in younger patients. DISCUSSION: LS is a disorder of older age group with female preponderance. It is a source of significant morbidity, and long-standing cases predispose to vulvar malignancy. CONCLUSION: To conclude, early diagnosis with proper counselling of the patient and his/her partner regarding various aspects of disease are essential for a wholesome approach. Wolters Kluwer - Medknow 2022 2022-06-07 /pmc/articles/PMC9282700/ /pubmed/35846549 http://dx.doi.org/10.4103/ijstd.ijstd_126_20 Text en Copyright: © 2022 Indian Journal of Sexually Transmitted Diseases and AIDS https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Brar, Sukhmani Kaur Bano, Rubeena Puri, Neerja Singh, Amarbir A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India |
title | A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India |
title_full | A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India |
title_fullStr | A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India |
title_full_unstemmed | A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India |
title_short | A study on clinical spectrum of lichen sclerosus in a tertiary care Centre in North India |
title_sort | study on clinical spectrum of lichen sclerosus in a tertiary care centre in north india |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282700/ https://www.ncbi.nlm.nih.gov/pubmed/35846549 http://dx.doi.org/10.4103/ijstd.ijstd_126_20 |
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