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From Transcriptomics, Metabolomics to Functional Studies: Extracellular ATP Induces TGF-β-Like Epithelial Mesenchymal Transition in Lung Cancer Cells

We and others previously showed that extracellular ATP (eATP) is implicated in epithelial mesenchymal transition (EMT). However, the mechanisms by which eATP induces EMT and ATP’s relationship to TGF-β, a well-known EMT inducer, are largely unclear. Also, eATP-induced EMT has never been studied at t...

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Detalles Bibliográficos
Autores principales: Evers, Maria, Song, Jingwen, Shriwas, Pratik, Greenbaum, Harrison S., Chen, Xiaozhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282887/
https://www.ncbi.nlm.nih.gov/pubmed/35847855
http://dx.doi.org/10.3389/fonc.2022.912065