KRAS mutations as essential promoters of lymphangiogenesis via extracellular vesicles in pancreatic cancer

Kirsten rat sarcoma virus (KRAS) gene mutations are present in more than 90% of pancreatic ductal adenocarcinomas (PDACs). KRAS(G12D) is the most frequent alteration, promoting preneoplastic lesions and associating with a more aggressive phenotype. These tumors possess increased intratumoral lymphat...

Descripción completa

Detalles Bibliográficos
Autores principales: Pirlog, Radu, Calin, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282924/
https://www.ncbi.nlm.nih.gov/pubmed/35838046
http://dx.doi.org/10.1172/JCI161454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282924/
https://www.ncbi.nlm.nih.gov/pubmed/35838046
http://dx.doi.org/10.1172/JCI161454

Ejemplares similares