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KRAS mutations as essential promoters of lymphangiogenesis via extracellular vesicles in pancreatic cancer
Kirsten rat sarcoma virus (KRAS) gene mutations are present in more than 90% of pancreatic ductal adenocarcinomas (PDACs). KRAS(G12D) is the most frequent alteration, promoting preneoplastic lesions and associating with a more aggressive phenotype. These tumors possess increased intratumoral lymphat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Clinical Investigation
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282924/ https://www.ncbi.nlm.nih.gov/pubmed/35838046 http://dx.doi.org/10.1172/JCI161454 |