Schwann cell nodal membrane disruption triggers bystander axonal degeneration in a Guillain-Barré syndrome mouse model

In Guillain-Barré syndrome (GBS), both axonal and demyelinating variants can be mediated by complement-fixing anti–GM1 ganglioside autoantibodies that target peripheral nerve axonal and Schwann cell (SC) membranes, respectively. Critically, the extent of axonal degeneration in both variants dictates...

Descripción completa

Detalles Bibliográficos
Autores principales: McGonigal, Rhona, Campbell, Clare I., Barrie, Jennifer A., Yao, Denggao, Cunningham, Madeleine E., Crawford, Colin L., Rinaldi, Simon, Rowan, Edward G., Willison, Hugh J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282931/
https://www.ncbi.nlm.nih.gov/pubmed/35671105
http://dx.doi.org/10.1172/JCI158524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282931/
https://www.ncbi.nlm.nih.gov/pubmed/35671105
http://dx.doi.org/10.1172/JCI158524

Ejemplares similares